Dual Fluorescent PARKIN-PINK1 Cell Line

Description Dual fluorescent PARKIN-PINK1 Cell Line is a U2OS stably engineered cell line. The cell line express both human PINK1 fused to green fluorescent protein (GFP) and human Parkin fused to red fluorescent protein (RFP). This dual-fluorescent system provides a powerful platform for studying mitophagy under physiological and stress-induced conditions. Under mitochondrial stress, PINK1 accumulates on the outer mitochondrial membrane and recruits Parkin, triggering mitophagy. By tagging PINK1 with green fluorescent protein (GFP) and Parkin with red fluorescent protein (RFP), this cell line allows researchers to monitor their localization, interaction, and translocation with high spatial and temporal resolution. Each vial of this Dual Fluorescent PARKIN-PINK1 Cell Line contains 3 million cells. We guarantee that these cells will expand in more than 30 passages following the cell culture manual.