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ABCE1 antibody

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Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Antagonizes the binding of 2-5A(5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. Immunogen: ATP-binding cassette, sub-family E(OABP), member 1 Synonyms: ABCE1, RLI, RNase L inhibitor, RNASEL1, OABP Observed MW: 50-70 kDa Uniprot ID: P61221 Reactivity: Human Tested Application: ELISA, WB, IHC Recommended dilution: WB: 1: 500-1: 2000; IHC: 1: 20-1: 200 Gene ID: 6059 Research Area: Metabolism

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Internal Reference: FNab10351