COX2 antibody

Volume: 100 µg Purification: protein A+G purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Mouse Clonality: monoclonal Clone ID: 4H7 Isotype: IgG2a Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. Immunogen: prostaglandin-endoperoxide synthase 2 Synonyms: COX 2, COX2, Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2 Observed MW: 68 kDa Uniprot ID: P35354 Reactivity: Human, Mouse Tested Application: ELISA, WB, IHC Recommended dilution: WB: 1: 500-1: 2000; IHC: 1: 100-1: 400 Gene ID: 5743 Research Area: Cancer, Cardiovascular, Metabolism