Cytochrome c antibody

Volume: 100 µg Purification: Protein A+G purification Form: liquid Purity: 95% as determined by SDS-PAGE Host: Mouse Clonality: monoclonal Clone ID: 3G4 Isotype: IgG2a Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy. Immunogen: Cytochrome c Synonyms: CYC, CYCS, Cytochrome c, cytochrome c, somatic, HCS, THC4 Observed MW: 12 kDa Uniprot ID: P99999 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IHC Recommended dilution: WB: 1: 5000-1: 30000; IHC: 1: 100-1: 1000 Gene ID: 54205 Research Area: Cardiovascular, Metabolism