CD150 antibody(PE conjugated)

Volume: 100 µg Purification: Protein G purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rat Clonality: monoclonal Clone ID: 3B6 Isotype: IgG1 Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signalinglymphocyte activation molecule) orIPO-3. CD150, asingle chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained onTh1 but notTh2 clones.Tregulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-g production byTh1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoieticstem cell studies. Immunogen: signaling lymphocytic activation molecule family member 1 Synonyms: CDw150, Slamf1, Slam, ESTM51, IPO-3, 4933415F16, AA177906 Observed MW: 11kd Uniprot ID: Q9QUM4 Reactivity: Mouse Tested Application: FC Recommended dilution: 1?10-1?50 Gene ID: Research Area: