DCK antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background: Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. Immunogen: deoxycytidine kinase Synonyms: Observed MW: 30 kDa Uniprot ID: P27707 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IHC, IF Recommended dilution: WB: 1: 500 - 1: 2000; IHC: 1: 50 - 1: 200; IF: 1: 50 - 1: 200 Gene ID: 1633 Research Area: Metabolism