Cytokeratin 18 antibody

Volume: 100 µg Purification: Protein A+G purification Form: liquid Purity: 95% as determined by SDS-PAGE Host: Mouse Clonality: monoclonal Clone ID: 6E3 Isotype: IgG2a Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas. Immunogen: keratin 18 Synonyms: CK 18, CYK18, Cytokeratin 18, K18, keratin 18, KRT18 Observed MW: 48 kDa Uniprot ID: P05783 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, FC, IF, IHC Recommended dilution: WB: 1: 5000-1: 30000; IHC: 1: 500-1: 1000; IF: 1: 100-1: 300 Gene ID: Research Area: Cancer, Immunology, Cardiovascular