Cysteine dioxygenase type 1 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: CDO1(cysteine dioxygenase type 1) is also named as CDO and belongs to the cysteine dioxygenase family. It is an enzyme that adds molecular oxygen to the sulfur of cysteine, converting the thiol to a sulfinic acid known as cysteinesulfinic acid(3-sulfinoalanine) and CDO1 is one of the most highly regulated metabolic enzymes responding to diet(PMID: 19011731). The expression of CDO can significantly decrease the level of intracellular cysteine and this reduction is also associated with a decrease in total glutathione levels(PMID: 17327371). Cysteine dioxygenase(CDO) plays a critical role in the regulation of cellular cysteine concentration andmultiple forms of CDO(23?kDa, 25?kDa, and 68?kDa) have been claimed based upon separation and detection using S Immunogen: cysteine dioxygenase, type I Synonyms: CDO, CDO I, CDO1, Cysteine dioxygenase type 1, cysteine dioxygenase, type I Observed MW: 23 kDa Uniprot ID: Q16878 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IHC, IP Recommended dilution: WB: 1: 200-1: 2000; IP: 1: 200-1: 2000; IHC: 1: 20-1: 200 Gene ID: Research Area: Signal Transduction, Metabolism