CYP4F3 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Isoform CYP4F3A: Catalyzes the omega-hydroxylation of leukotriene-B(4), a potent chemoattractant for polymorphonuclear leukocytes, it has low activity for arachidonic acid. Isoform CYP4F3B: Shows arachidonic acid omega-hydroxylase activity by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid(20-HETE)(PubMed: 11461919, PubMed: 16820285). Has a 30-fold higher Km for leukotriene-B(4) compared with CYP4F3A(PubMed: 11461919). Also converts eicosapentaenoate(EPA) to 20-hydroxyeicosapentaenoate(20-OH-EPA)(PubMed: 16820285). Acts as a polyunsaturated omega-3 fatty acids hydroxylase: mediates conversion of docosahexaenoate(DHA) to 22-hydroxydocosahexaenoate(PubMed: 16820285). Immunogen: cytochrome P450, family 4, subfamily F, polypeptide 3 Synonyms: LTB4H Observed MW: 60 kDa Uniprot ID: Q08477 Reactivity: Human Tested Application: ELISA, WB Recommended dilution: WB: 1: 500-1: 2000 Gene ID: 4051 Research Area: Metabolism