CYP2C8 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15-and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti-cancer drug paclitaxel(taxol). Immunogen: cytochrome P450, family 2, subfamily C, polypeptide 8 Synonyms: CPC8, CYP2C8, CYPIIC8, Cytochrome P450 2C8 Observed MW: Uniprot ID: P10632 Reactivity: Human Tested Application: ELISA, IHC Recommended dilution: IHC: 1: 500-1: 1000 Gene ID: 1558 Research Area: Metabolism