CREM antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Transcriptional regulator that binds the cAMP response element(CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation(PubMed: 10373550). Isoform 6: May play a role in the regulation of the circadian clock: acts as a transcriptional repressor of the core circadian component PER1 by directly binding to cAMP response elements in its promoter. Immunogen: cAMP responsive element modulator Synonyms: CREM, hCREM 2, ICER, Inducible cAMP early repressor Observed MW: 36 kDa Uniprot ID: Q03060 Reactivity: Human, Mouse, Rat Tested Application: ELISA, IHC, WB Recommended dilution: WB: 1: 500 - 1: 2000; IHC: 1: 50 - 1: 200 Gene ID: 1390 Research Area: Neuroscience, Signal Transduction, Metabolism, Developmental biology