CPNE1 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes(PubMed: 14674885). Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner(PubMed: 14674885). Exhibits calcium-dependent phospholipid binding properties(PubMed: 9430674, PubMed: 19539605). Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner(PubMed: 23263657, PubMed: 25450385). May recruit target proteins to the cell membrane in a calcium-dependent manner(PubMed: 12522145). May function in membrane trafficking(PubMed: 9430674). Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit(PubMed: 18212740). Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL(PubMed: 18212740). Immunogen: copine I Synonyms: CPN1 Observed MW: Uniprot ID: Q99829 Reactivity: Human Tested Application: ELISA Recommended dilution: Gene ID: 8904 Research Area: Metabolism