CPLX1 antibody
Volume: 100 µg
Purification: Immunogen affinity purified
Form: liquid
Purity: 95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID:
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background: Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles(PubMed: 21785414). Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse(PubMed: 21785414). Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.
Immunogen: complexin 1
Synonyms: complexin 1, Complexin I, complexin1, CPLX1, CPX I, CPX1, Synaphin 2
Observed MW: 15-20 kDa
Uniprot ID: O14810
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1: 500-1: 5000; IHC: 1: 20-1: 200; IF: 1: 10-1: 100
Gene ID: 10815
Research Area: Neuroscience
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Internal Reference:
FNab01920
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