COMMD5 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: May modulate activity of cullin-RING E3 ubiquitin ligase(CRL) complexes(PubMed: 21778237). Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis(By similarity). Down-regulates activation of NF-kappa-B(PubMed: 15799966). Immunogen: COMM domain containing 5 Synonyms: Observed MW: 25-28 kDa Uniprot ID: Q9GZQ3 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IP Recommended dilution: WB: 1: 500-1: 2000; IP: 1: 200-1: 2000 Gene ID: 54951 Research Area: Signal Transduction, Metabolism, Epigenetics