CNGA3 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3(By similarity). Essential for the generation of light-evoked electrical responses in the red-, green-and blue sensitive cones. Immunogen: cyclic nucleotide gated channel alpha 3 Synonyms: CNCG3 Observed MW: 98 kDa Uniprot ID: Q16281 Reactivity: Human Tested Application: ELISA, WB Recommended dilution: WB: 1: 500-1: 2000 Gene ID: 1261 Research Area: Neuroscience, Signal Transduction