CLEC4M antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. (Microbial infection) Acts as an attachment receptor for ebola virus(PubMed: 12050398, PubMed: 12502850). Acts as an attachment receptor for hepatitis C virus(PubMed: 15371595, PubMed: 16816373). Acts as an attachment receptor for HIV-1(PubMed: 21277928, PubMed: 12502850). Acts as an attachment receptor for human coronavirus 229E(PubMed: 17037540). Acts as an attachment receptor for human cytomegalovirus/HHV-5(PubMed: 12433371). Acts as an attachment receptor for influenzavirus(PubMed: 21191006). Acts as an attachment receptor for SARS coronavirus(PubMed: 15479853). Acts as an attachment receptor for west-nile virus(PubMed: 16415006). Acts as an attachment receptor for Japanese encephalitis virus(PubMed: 24623090). Acts as an attachment receptor for Marburg virus glycoprotein(PubMed: 15479853). Recognition of M.bovis by dendritic cells may occur partially via this molecule(PubMed: 21203928). Immunogen: C-type lectin domain family 4, member M Synonyms: CD209L, CD209L1, CD299 Observed MW: Uniprot ID: Q9H2X3 Reactivity: Human Tested Application: ELISA, IHC, WB Recommended dilution: WB: 1: 500-1: 2000; IHC: 1: 20-1: 200 Gene ID: 10332 Research Area: Immunology, Cardiovascular, Signal Transduction