CHRNA10 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. Immunogen: cholinergic receptor, nicotinic, alpha 10 Synonyms: NACHRA10 Observed MW: 50-52 kDa Uniprot ID: Q9GZZ6 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB Recommended dilution: WB: 1: 500-1: 2000 Gene ID: 57053 Research Area: Neuroscience