CD68 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. Immunogen: CD68 molecule Synonyms: CD68, CD68 molecule, DKFZp686M18236, GP110, Macrosialin, SCARD1 Observed MW: Refer to figures Uniprot ID: P34810 Reactivity: Human, Mouse Tested Application: ELISA, IHC, WB Recommended dilution: WB: 1: 500 - 1: 2000; IHC: 1: 50 - 1: 200 Gene ID: 968 Research Area: Neuroscience, Stem Cells, Immunology, Cancer