CD63 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. Immunogen: CD63 molecule Synonyms: MLA1, TSPAN30 Observed MW: 53 kDa Uniprot ID: P08962 Reactivity: Human, Mouse, Rat Tested Application: ELISA, IHC, WB Recommended dilution: WB: 1: 500 - 1: 2000; IHC: 1: 50 - 1: 200 Gene ID: 967 Research Area: Cancer, Immunology, Cardiovascular, Signal Transduction