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Cd2ap antibody

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Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis. Immunogen: CD2-associated protein Synonyms: Observed MW: 70 kDa Uniprot ID: Q9Y5K6 Reactivity: Human, Mouse Tested Application: ELISA, WB, IF, IP Recommended dilution: WB: 1: 500-1: 2000; IP: 1: 500-1: 1000; IF: 1: 10-1: 100 Gene ID: 23607 Research Area: Signal Transduction

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Internal Reference: FNab01455

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