CCT4 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background: The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]). Immunogen: chaperonin containing TCP1, subunit 4 (delta) Synonyms: CCTD, SRB Observed MW: 60 kDa Uniprot ID: P50991 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IHC, IF Recommended dilution: WB: 1: 500 - 1: 2000; IHC: 1: 50 - 1: 200; IF: 1: 50 - 1: 200 Gene ID: 10575 Research Area: Neuroscience, Metabolism