CCNY antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription. Immunogen: cyclin Y Synonyms: C10orf9, CBCP1, CFP1 Observed MW: 33-39 kDa Uniprot ID: Q8ND76 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IF, IP Recommended dilution: WB: 1: 500-1: 2000; IP: 1: 500-1: 1000; IF: 1: 10-1: 100 Gene ID: 219771 Research Area: Stem Cells