CBS antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine(PubMed: 23981774, PubMed: 20506325, PubMed: 23974653). Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons(By similarity). Immunogen: cystathionine-beta-synthase Synonyms: Beta thionase, CBS, cystathionine beta synthase, HIP4, Serine sulfhydrase Observed MW: 61 kDa Uniprot ID: P35520 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IHC, IF, IP Recommended dilution: WB: 1: 500-1: 2000; IP: 1: 500-1: 1000; IHC: 1: 50-1: 200; IF: 1: 20-1: 200 Gene ID: 875 Research Area: Metabolism