CARD11 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. Immunogen: caspase recruitment domain family, member 11 Synonyms: CARMA1 Observed MW: 133 kDa Uniprot ID: Q9BXL7 Reactivity: Human, Mouse, Rat Tested Application: ELISA, WB, IF, IHC Recommended dilution: WB: 1: 500-1: 2000; IHC: 1: 20-1: 200; IF: 1: 20-1: 200 Gene ID: 84433 Research Area: Immunology, Signal Transduction