CAMKK2 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase(AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals(By similarity). Seems to be involved in hippocampal activation of CREB1(By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching. Immunogen: calcium/calmodulin-dependent protein kinase kinase 2, beta Synonyms: CAMKKB, KIAA0787 Observed MW: 55-60 kDa Uniprot ID: Q96RR4 Reactivity: Human, Mouse Tested Application: ELISA, WB, IF, IHC Recommended dilution: WB: 1: 500-1: 2000; IF: 1: 20-1: 200; IHC: 1: 20-1: 200 Gene ID: 10645 Research Area: Neuroscience, Signal Transduction, Metabolism