Aldolase C antibody

Volume: 100 µg Purification: Protein A+G purification Form: liquid Purity: 95% as determined by SDS-PAGE Host: Mouse Clonality: monoclonal Clone ID: 6F3 Isotype: IgG1 Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID: 9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID: 21548097). Immunogen: aldolase C, fructose-bisphosphate Synonyms: ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C Observed MW: 39 kDa Uniprot ID: P09972 Reactivity: Human Tested Application: ELISA, WB, IHC, IF Recommended dilution: WB: 1: 5000-1: 50000; IHC: 1: 50-1: 500; IF: 1: 20-1: 200 Gene ID: 230 Research Area: Metabolism