ACVRL1 antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well. Immunogen: activin A receptor type II-like 1 Synonyms: Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I Observed MW: 56 kDa Uniprot ID: P37023 Reactivity: Human Tested Application: ELISA, WB, IHC, FC, IP Recommended dilution: WB: 1: 200-1: 1000; IHC: 1: 100-1: 400; IP: 1: 200-1: 1000 Gene ID: 94 Research Area: Cardiovascular, Metabolism, Signal Transduction