5 Lipoxygenase antibody

Volume: 100 µg Purification: Immunogen affinity purified Form: liquid Purity: 95% as determined by SDS-PAGE Host: Rabbit Clonality: polyclonal Clone ID: Isotype: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background: ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene(cys-LT) production, critical mediators in asthma(PMID: 12911785). Immunogen: arachidonate 5-lipoxygenase Synonyms: 5 Lipoxygenase, 5 LO, 5 LOX, 5LPG, ALOX5, LOG5 Observed MW: 68-78 kDa Uniprot ID: P09917 Reactivity: Human, Mouse, Rat Tested Application: ELISA, IF, WB Recommended dilution: WB: 1: 200-1: 2000; IF: 1: 20-1: 100 Gene ID: Research Area: Metabolism