CD47 Antibody

Size : 50 µL Clone Number: 4G11 Aliases: Leukocyte surface antigen CD47 (Antigenic surface determinant protein OA3) (Integrin-associated protein) (IAP) (Protein MER6) (CD antigen CD47), CD47, MER6 Product Type: Recombinant Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q08722 Immunogen: A synthesized peptide derived from human CD47 Host: Reactivity: Human Tested Applications: ELISA, WB, IHC, IF; Recommended dilution: WB: 1: 500-1: 5000, IHC: 1: 50-1: 200, IF: 1: 20-1: 200 Background: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. Clonality: Monoclonal Isotype: Rabbit IgG Purification Method: Affinity-chromatography Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CD47 Research Areas: Cancer; Immunology