DBF4 Antibody

Size : 50 µL Clone Number: 24D8 Aliases: Protein DBF4 homolog A (Activator of S phase kinase) (Chiffon homolog A) (DBF4-type zinc finger-containing protein 1), DBF4, ASK DBF4A ZDBF1 Product Type: Recombinant Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9UBU7 Immunogen: A synthesized peptide derived from human DBF4 Host: Reactivity: Human Tested Applications: ELISA, WB, IF Recommended dilution: WB: 1: 500-1: 2000, IF: 1: 50-1: 200 Background: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. {ECO: 0000269|PubMed: 10373557, ECO: 0000269|PubMed: 10523313, ECO: 0000269|PubMed: 17062569}. Clonality: Monoclonal Isotype: Rabbit IgG Purification Method: Affinity-chromatography Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: DBF4 Research Areas: Epigenetics and Nuclear Signaling; Cell biology