CCNL1 Antibody

Size : 100 µL Clone Number: Aliases: CCNL1 antibody; BM-001 antibody; UNQ530/PRO1073 antibody; Cyclin-L1 antibody; Cyclin-L antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9UK58 Immunogen: Synthesized peptide derived from Human Cyclin-L1. Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 3000, IHC: 1: 50-1: 100 Background: Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21. A. Hamid Boulares, J. Biol. Chem., Aug 1999; 274: 22932. Alessandra Pagano, Am J Physiol Lung Cell Mol Physiol, Jun 2007; 10.1152. Mi Young Kim, Genes & Dev., Sep 2005; 19: 1951 - 1967. Silke S?e, Nucleic Acids Res., Feb 2004; 32: 669 - 680. Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CCNL1 Research Areas: Epigenetics and Nuclear Signaling