CHRNA7 Antibody

Size : 50 µL Clone Number: Aliases: 7nAChR antibody; a7 nicotinic acetylcholine receptor antibody; acetylcholine receptor; neuronal nicotinic; alpha-7 subunit antibody; ACHA7_HUMAN antibody; AChR antibody; Acra7 antibody; alpha 7 neuronal nicotinic acetylcholine receptor antibody; alpha-7 nicotinic cholinergic receptor subunit antibody; alpha7 antibody; cholinergic receptor; neuronal nicotinic; alpha polypeptide 7 antibody; cholinergic receptor; nicotinic; alpha 7 (neuronal) antibody; cholinergic receptor; nicotinic; alpha 7 antibody; cholinergic receptor; nicotinic; alpha polypeptide 7 antibody; CHRNA7 antibody; CHRNA7-2 antibody; NACHRA7 antibody; neuronal acetylcholine receptor protein; alpha-7 chain antibody; Neuronal acetylcholine receptor subunit alpha-7 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P36544 Immunogen: Synthetic peptide of Human CHRFAM7A Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 500-1: 2000, IHC: 1: 25-1: 100 Background: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CHRNA7 Research Areas: Others