CYP46A1 Antibody

Size : 50 µL Clone Number: Aliases: CYP46A1 antibody; CYP46Cholesterol 24-hydroxylase antibody; CH24H antibody; EC 1.14.14.25 antibody; Cholesterol 24-monooxygenase antibody; Cholesterol 24S-hydroxylase antibody; Cytochrome P450 46A1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9Y6A2 Immunogen: Synthetic peptide of Human CYP46A1 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; ELISA: 1: 1000-1: 2000, WB: 1: 200-1: 1000, IHC: 1: 25-1: 100 Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CYP46A1 Research Areas: Others