ADAM15 Antibody

Size : 50 µL Clone Number: Aliases: A disintegrin and metalloproteinase domain 15 (metargidin) antibody; A disintegrin and metalloproteinase domain 15 antibody; ADA15_HUMAN antibody; ADAM 15 antibody; ADAM metallopeptidase domain 15 antibody; Adam15 antibody; and cysteine-rich protein 15 antibody; Disintegrin and metalloproteinase domain-containing protein 15 antibody; disintegrin-like antibody; EC 3.4.24. antibody; MDC 15 antibody; MDC-15 antibody; MDC15 antibody; Metalloprotease RGD disintegrin protein antibody; Metalloproteinase like disintegrin like and cysteine rich protein 15 antibody; Metalloproteinase-like antibody; Metargidin antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q13444 Immunogen: Fusion protein of Human ADAM15 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 25-1: 100 Background: The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ADAM15 Research Areas: Cancer;Cell biology;Signal transduction