CERK Antibody

Size : 50 µL Clone Number: Aliases: Acylsphingosine kinase antibody; Ceramide kinase antibody; Cerk antibody; CERK1_HUMAN antibody; dA59H18.2 antibody; dA59H18.3 antibody; hCERK antibody; KIAA1646 antibody; Lipid kinase 4 antibody; Lipid kinase LK4 antibody; LK4 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q8TCT0 Immunogen: Fusion protein of Human CERK Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 5000, IHC: 1: 25-1: 100 Background: CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CERK Research Areas: Cell biology