CORIN Antibody

Size : 50 µL Clone Number: Aliases: activated protease fragment antibody; ATC 2 antibody; ATC2 antibody; Atrial natriuretic peptide-converting enzyme antibody; Atrial natriuteric peptide converting enzyme antibody; Corin antibody; Corin serine peptidase antibody; CORIN_HUMAN antibody; CRN antibody; Heart specific serine proteinase antibody; Heart specific serine proteinase ATC2 antibody; Heart-specific serine proteinase ATC2 antibody; MGC119742 antibody; Pro ANP convertase antibody; Pro ANP converting enzyme antibody; Pro-ANP-converting enzyme antibody; TMPRSS 10 antibody; TMPRSS10 antibody; Transmembrane protease serine 10 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9Y5Q5 Immunogen: Recombinant Human Atrial natriuretic peptide-converting enzyme protein (1-110AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 20-1: 200 Background: Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CORIN Research Areas: Cardiovascular; Cell biology