CD207 Antibody

Size : 50 µg Clone Number: Aliases: C type lectin domain family 4 member K antibody; C-type lectin domain family 4 member K antibody; CD 207 antibody; CD207 antibody; CD207 antigen antibody; CD207 antigen; langerin antibody; CD207 molecule antibody; CLC4K_HUMAN antibody; CLEC 4K antibody; CLEC4K antibody; Langerhans cell specific c type lectin antibody; Langerin antibody; RGD1565913 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9UJ71 Immunogen: Recombinant Human C-type lectin domain family 4 member K protein (229-312AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC, IF; Recommended dilution: IHC: 1: 20-1: 200, IF: 1: 50-1: 200 Background: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Non-conjugated Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CD207 Research Areas: Tags & Cell Markers; Signal transduction