CYP21A2 Antibody

Size : 50 µL Clone Number: Aliases: CYP21 antibody; 21 OHase antibody; 21-OHase antibody; CA21H antibody; CAH1 antibody; CP21A_HUMAN antibody; CPS1 antibody; CYP21A 2 antibody; CYP21A2 antibody; CYP21B antibody; Cytochrome P-450c21 antibody; Cytochrome P450 21 antibody; Cytochrome P450 C21B antibody; Cytochrome P450 XXI antibody; Cytochrome P450; family 21; subfamily A; polypeptide 2 antibody; Cytochrome P450; subfamily XXIA (steroid 21 hydroxylase; congenital adrenal hyperplasia); polypeptide 2 antibody; Cytochrome P450-C21 antibody; Cytochrome P450-C21B antibody; P450 C21 antibody; P450 C21B antibody; P450c21B antibody; Steroid 21 hydroxylase antibody; Steroid 21 monooxygenase antibody; Steroid 21-hydroxylase antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: P08686 Immunogen: Fusion protein of Human CYP21A2 Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 200-1: 1000, IHC: 1: 50-1: 200 Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CYP21A2 Research Areas: Cancer Cardiovascular;Metabolism;Signal transduction