CHRNA9 Antibody

Size : 50 µL Clone Number: Aliases: CHRNA9 antibody; NACHRA9Neuronal acetylcholine receptor subunit alpha-9 antibody; Nicotinic acetylcholine receptor subunit alpha-9 antibody; NACHR alpha-9 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9UGM1 Immunogen: Recombinant Human Neuronal acetylcholine receptor subunit alpha-9 protein (26-240AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 20-1: 200 Background: Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane (PubMed: 11752216, PubMed: 25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane (PubMed: 11752216, PubMed: 25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regulate keratinocyte adhesion (PubMed: 11021840). Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CHRNA9 Research Areas: Neuroscience