ACIN1 Antibody

Size : 50 µL Clone Number: Aliases: ACIN 1 antibody; ACIN1 antibody; ACINU_HUMAN antibody; Acinus antibody; ACN antibody; Apoptotic chromatin condensation inducer 1 antibody; Apoptotic chromatin condensation inducer in the nucleus antibody; DKFZp667N107 antibody; fSAP152 antibody; functional spliceosome-associated protein 152 antibody; KIAA0670 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9UKV3 Immunogen: Synthetic peptide of Human ACIN1 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, IHC; ELISA: 1: 2000-1: 10000, IHC: 1: 100-1: 300 Background: Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: ACIN1 Research Areas: Epigenetics and Nuclear Signaling;Cancer;Cell biology;Metabolism