CHCHD3 Antibody

Size : 50 µL Clone Number: Aliases: CHCH3_HUMAN antibody; CHCHD 3 antibody; Chchd3 antibody; Coiled coil helix coiled coil helix domain containing 3 antibody; Coiled coil helix coiled coil helix domain containing protein 3 mitochondrial antibody; Coiled-coil-helix-coiled-coil-helix domain-containing protein 3 antibody; FLJ20420 antibody; MINOS3 antibody; mitochondrial antibody; Mitochondrial inner membrane organizing system 3 antibody; PPP1R22 antibody; Protein phosphatase 1 regulatory subunit 22 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9NX63 Immunogen: Recombinant Human MICOS complex subunit MIC19 protein (1-227AA) Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; Recommended dilution: WB: 1: 1000-1: 5000, IHC: 1: 20-1: 200 Background: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed: 25781180). Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CHCHD3 Research Areas: Tags & Cell Markers; Metabolism; Signal transduction