CAV1 Antibody

Size : 100 µL Clone Number: Aliases: BSCL3 antibody; CAV antibody; CAV1 antibody; CAV1_HUMAN antibody; caveolae protein, 22 kD antibody; caveolin 1 alpha isoform antibody; caveolin 1 beta isoform antibody; Caveolin 1 caveolae protein 22kDa antibody; Caveolin-1 antibody; Caveolin1 antibody; cell growth-inhibiting protein 32 antibody; CGL3 antibody; LCCNS antibody; MSTP085 antibody; OTTHUMP00000025031 antibody; PPH3 antibody; VIP 21 antibody; VIP21 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q03135 Immunogen: Synthesized peptide derived from Human Caveolin-1. Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IF; WB: 1: 500-1: 3000, IF: 1: 100-1: 500 Background: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity By similarity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. Wei Zhang, J. Biol. Chem., Jun 2000; 275: 20717. Rosalia Mora, J. Biol. Chem., Sep 1999; 274: 25708. Isabella Parolini, J. Biol. Chem., Sep 1999; 274: 25718. Phuong U. Le, J. Biol. Chem., Jan 2002; 277: 3371 - 3379. Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CAV1 Research Areas: Cancer Cardiovascular;Tags & Cell Markers;Metabolism;Signal transduction