CHRDL1 Antibody, Biotin conjugated

Size : 50 µg Clone Number: Aliases: CHL antibody; chordin like 1 antibody; Chordin-like protein 1 antibody; CHRDL1 antibody; CRDL1_HUMAN antibody; dA141H5.1 antibody; neuralin 1 antibody; Neuralin-1 antibody; Neurogenesin-1 antibody; NRLN1 antibody; Ventroptin antibody; VOPT antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9BU40 Immunogen: Recombinant Human Chordin-like protein 1 protein (92-237AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development. Clonality: Polyclonal Isotype: IgG Purification Method: 95%, Protein G purified Conjugate: Biotin Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CHRDL1 Research Areas: Neuroscience; Stem cells