CCM2 Antibody

Size : 50 µL Clone Number: Aliases: C7orf22 antibody; Ccm2 antibody; CCM2 gene antibody; CCM2_HUMAN antibody; Cerebral cavernous malformation 2 antibody; Cerebral cavernous malformations 2 protein antibody; Chromosome 7 open reading frame 22 antibody; Malcavernin antibody; MGC4067 antibody; MGC4607 antibody; MGC74868 antibody; OSM antibody; Osmosensing scaffold for MEKK3 antibody; OTTHUMP00000159554 antibody; OTTHUMP00000214270 antibody; OTTHUMP00000214271 antibody; OTTHUMP00000214273 antibody; PP10187 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9BSQ5 Immunogen: Recombinant Human Cerebral cavernous malformations 2 protein (1-300AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, IHC; Recommended dilution: IHC: 1: 20-1: 200 Background: Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity). Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CCM2 Research Areas: Neuroscience; Signal transduction