CPNE1 Antibody, Biotin conjugated

Size : 50 µL Clone Number: Aliases: Copine 1 antibody; Copine I antibody; Copine-1 antibody; Copine1 antibody; CopineI antibody; COPN 1 antibody; COPN1 antibody; CPN 1 antibody; CPN1 antibody; CPNE 1 antibody; CPNE1 antibody; CPNE1_HUMAN antibody; MGC1142 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q99829 Immunogen: Recombinant Human Copine-1 protein (326-537AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA Background: Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes (PubMed: 14674885). Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner (PubMed: 14674885). Exhibits calcium-dependent phospholipid binding properties (PubMed: 9430674, PubMed: 19539605). Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner (PubMed: 23263657, PubMed: 25450385). May recruit target proteins to the cell membrane in a calcium-dependent manner (PubMed: 12522145). May function in membrane trafficking (PubMed: 9430674). Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit (PubMed: 18212740). Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL (PubMed: 18212740). Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Biotin Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CPNE1 Research Areas: Signal transduction