CBX8 Antibody

Size : 50 µL Clone Number: Aliases: Cbx8 antibody; CBX8_HUMAN antibody; Chromobox Homolog 8 (Drosophila Pc Class) antibody; Chromobox Homolog 8 (Pc Class Homolog; Drosophila) antibody; Chromobox Homolog 8 antibody; Chromobox protein homolog 8 antibody; hPc3 antibody; Pc Class 3 Homolog (Drosophila) antibody; Pc Class 3 Homolog antibody; Pc3 antibody; Polycomb 3 antibody; Polycomb 3 homolog antibody; RC1 antibody; Rectachrome 1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9HC52 Immunogen: Fusion protein of Human CBX8 Host: Rabbit Reactivity: Human, Mouse Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 5000, WB: 1: 500-1: 2000, IHC: 1: 10-1: 50 Background: Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.CBX8 has been shown to interact with RING1 and MLLT1.Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CBX8 Research Areas: Epigenetics and Nuclear Signaling