CCAR1 Antibody

Size : 50 µL Clone Number: Aliases: CARP-1 antibody; Carp1 antibody; Ccar1 antibody; CCAR1_HUMAN antibody; Cell cycle and apoptosis regulatory protein 1 antibody; cell division cycle and apoptosis regulator 1 antibody; Cell division cycle and apoptosis regulator protein 1 antibody; Death inducer with SAP domain antibody; FLJ10590 antibody; FLJ10839 antibody; FLJ13376 antibody; FLJ20734 antibody; MGC7730 antibody; RP11-437A18.1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q8IX12 Immunogen: Recombinant Human Cell division cycle and apoptosis regulator protein 1 protein (1-200AA) Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; Recommended dilution: WB: 1: 500-1: 2000, IHC: 1: 20-1: 200 Background: Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen Affinity Purified Conjugate: Non-conjugated Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CCAR1 Research Areas: Epigenetics and Nuclear Signaling; Cancer; Cell biology; Metabolism