CTNND1 (Ab-228) Antibody

Size : 100 µL Clone Number: Aliases: Cadherin associated Src substrate antibody; Cadherin-associated Src substrate antibody; CAS antibody; Catenin (cadherin associated protein) delta 1 antibody; Catenin delta 1 antibody; Catenin delta antibody; Catenin delta-1 antibody; CTND1_HUMAN antibody; CTNND 1 antibody; CTNND antibody; CTNND1 antibody; delta 1 Catenin antibody; KIAA0384 antibody; p120 antibody; P120 CAS antibody; p120 catenin antibody; P120 CTN antibody; p120(cas) antibody; p120(ctn) antibody; P120CAS antibody; P120CTN antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O60716 Immunogen: Synthesized non-phosphopeptide derived from Human Catenin-?1 around the phosphorylation site of tyrosine 228 (D-N-Y(p)-G-S). Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 3000, IHC: 1: 50-1: 100 Background: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway By similarity. Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.Keirsebilck A., Genomics 50: 129-146(1998).Nagase T., DNA Res. 4: 141-150(1997).W.S., Sherwood J.K., Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases. Clonality: Polyclonal Isotype: IgG Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CTNND1 Research Areas: Signal transduction?Stem cells