CD2AP Antibody

Size : 50 µL Clone Number: Aliases: Adapter protein CMS antibody; AL024079 antibody; C78928 antibody; Cas ligand with multiple SH3 domains antibody; CD2 associated protein antibody; CD2-associated protein antibody; CD2AP antibody; CD2AP_HUMAN antibody; CMS antibody; Mesenchyme to epithelium transition protein with SH3 domains 1 antibody; METS 1 antibody; Mets1 antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: Q9Y5K6 Immunogen: Synthetic peptide of Human CD2AP Host: Rabbit Reactivity: Human Tested Applications: ELISA, WB, IHC; ELISA: 1: 2000-1: 10000, WB: 1: 1000-1: 5000, IHC: 1: 100-1: 300 Background: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. Clonality: Polyclonal Isotype: IgG Purification Method: Antigen affinity purification Conjugate: Non-conjugated Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form: Liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CD2AP Research Areas: Signal transduction