CLDN1 Antibody

Size : 100 µL Clone Number: Aliases: Claudin-1 antibody; Claudin1 antibody; CLD 1 antibody; CLD1 antibody; CLD1_HUMAN antibody; CLDN 1 antibody; Cldn1 antibody; ILVASC antibody; SEMP 1 antibody; SEMP1 antibody; Senescence associated epithelial membrane protein 1 antibody; Senescence associated epithelial membrane protein antibody; Senescence-associated epithelial membrane protein antibody Product Type: Polyclonal Antibody Immunogen Species: Homo sapiens (Human) UniProt ID: O95832 Immunogen: A synthesized peptide derived from Human Claudin 1 Host: Rabbit Reactivity: Human, Mouse, Rat Tested Applications: ELISA, WB, IHC; WB: 1: 500-1: 2000, IHC: 1: 50-1: 200 Background: Claudin 1 Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Acts as a co- receptor for HCV entry into hepatic cells. Belongs to the claudin family. Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN3, but not CLDN2, homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ and INADL. May interact with HCV E1 and E2 proteins. Clonality: Polyclonal Isotype: IgG Purification Method: Affinity-chromatography Conjugate: Non-conjugated Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt Form: liquid Stroage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names: CLDN1 Research Areas: Signal transduction